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Inner Ear fluids - Perilymph and Endolymph

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๐Ÿ’ง Inner Ear Fluids โ€” Endolymph & Perilymph

In this post, we'll cover a short but important topic โ€” the two fluids of the inner ear, their differences, composition, and how they are formed and absorbed.

๐Ÿ”น Overview

The inner ear contains two main fluids:

  • Perilymph
  • Endolymph

They differ in composition, location, and origin.


๐ŸŒ€ Perilymph

  • Composition: Resembles extracellular fluid โ†’ Rich in sodium ions (Naโบ)

  • Location: Fills the space between the bony and membranous labyrinth

  • Connection with CSF:

    • Communicates with cerebrospinal fluid (CSF) via the aqueduct of cochlea
    • This duct opens into the scala tympani, near the round window
    • It contains connective tissue resembling arachnoid, through which perilymph percolates

๐Ÿ’ญ Theories of Formation

  1. Filtrate of Blood Serum

    โ†’ Formed by capillaries of the spiral ligament

  2. Direct Continuation of CSF

    โ†’ Reaches the labyrinth via the aqueduct of cochlea


๐ŸŒŠ Endolymph

  • Composition: Resembles intracellular fluid
    โ†’ Rich in potassium ions (Kโบ)

  • Location: Fills the entire membranous labyrinth

๐Ÿงช Secreted By:

  • Stria vascularis of the cochlea

  • Dark cells of:

    • Utricle
    • Ampullated ends of semicircular ducts

๐Ÿ’ญ Theories of Flow

  1. Longitudinal Flow

    • Endolymph from cochlea travels through ductus reuniens โ†’ saccule โ†’ utricle โ†’ endolymphatic duct

    • Absorbed by the endolymphatic sac in the subdural space

  2. Radial Flow

    • Endolymph is secreted and absorbed by the stria vascularis itself

    • Assumes that the endolymphatic sac is vestigial in humans and plays no role in absorption

โš ๏ธ Note: These two views are still debated โ€” both are important to know.


๐Ÿ“Š Comparison Table

FeatureEndolymphPerilymph
LocationInside membranous labyrinthBetween bony and membranous labyrinth
Ionic CompositionHigh Kโบ (Potassium)High Naโบ (Sodium)
ResemblesIntracellular fluidExtracellular fluid / CSF
Protein ContentLowerHigher
Glucose ContentLowerHigher
FormationSecreted by stria vascularis & dark cellsEither from blood (spiral ligament) or CSF
AbsorptionBy endolymphatic sac or stria vascularisPercolates through cochlear aqueduct

๐Ÿ“Œ Summary

  • Perilymph: Sodium-rich, surrounds membranous labyrinth, resembles CSF
  • Endolymph: Potassium-rich, fills membranous labyrinth, essential for hair cell function
  • Both fluids have distinct origins and roles in hearing and balance
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