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Guttman Sign Explained | Nose, Larynx and Thyroid

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Guttman Sign Explained - Nose, Larynx & Thyroid

One of the most confusing eponyms in ENT is Guttman Sign, because it refers to three entirely different clinical findings in three different subspecialties:

  • Nose
  • Larynx
  • Thyroid

Guttman Sign (Nose)

๐Ÿ“Œ Type of Sign

๐Ÿ‘‰ Clinical sign

๐Ÿ” What is the Sign?

  • Development of ipsilateral nasal stuffiness or congestion

  • Occurs after a successful stellate ganglion block

โญ Indicates that the sympathetic block has worked.

๐Ÿง  Why does it occur?

  • Stellate ganglion block causes sympathetic denervation

  • Loss of sympathetic tone leads to:

    • Vasodilatation
    • Increased nasal mucosal congestion
  • As a result, the patient develops:

    • Ipsilateral nasal obstruction
    • Nasal stuffiness

๐Ÿ‘จโ€โš•๏ธ Eponym

Named after Guttman, who described nasal congestion as a marker of successful sympathetic blockade.

What is the most important sign of successful stellate ganglion block?

What is the classical triad of Horner syndrome?

What is the earliest indicator of successful stellate ganglion block?

What is the Stellate Ganglion?


Guttman Sign (Larynx)

๐Ÿ“Œ Type of Sign

๐Ÿ‘‰ Clinical test

Used for detecting Superior laryngeal nerve palsy.

๐Ÿ” What is the Sign?

Abnormal pitch changes produced when pressure is applied over the thyroid cartilage during phonation.

๐Ÿฉบ How is it elicited?

  1. Ask the patient to sustain a vowel sound (e.g. "eeee")

  2. Apply pressure over the thyroid cartilage:

    • Laterally
    • Anteriorly
  3. Observe the resulting pitch changes

๐ŸŽต Normal Response

Direction of PressureNormal Response
Lateral pressureIncrease in pitch
Anterior pressureDecrease in pitch

๐Ÿšจ Response in Superior Laryngeal Nerve Palsy

The normal response becomes reversed.

This reversal constitutes the Guttman Test.

๐Ÿง  Why does it occur?

The external branch of the superior laryngeal nerve supplies the Cricothyroid muscle.

The cricothyroid muscle is responsible for:

  • Increasing vocal cord tension
  • Controlling pitch of voice

Paralysis causes abnormal pitch modulation resulting in reversal of the expected response.

๐Ÿ‘จโ€โš•๏ธ Eponym

Named after Guttman, who described this pressure induced pitch reversal.

What is the commonest ENT cause of Superior Laryngeal Nerve Palsy?


Guttman Sign (Thyroid)

๐Ÿ“Œ Type of Sign

๐Ÿ‘‰ Clinical sign

Detected bycAuscultation of thyroid gland.

๐Ÿ” What is the Sign?

Presence of a Thyroid bruit.

Most classically heard in Graves disease.

๐Ÿง  Why does it occur?

In Graves disease there is:

  • Increased vascularity
  • Increased blood flow

This creates turbulent blood flow producing Systolic thyroid bruit.

๐Ÿฉบ How is it elicited?

  1. Ask the patient to hold their breath
  2. Auscultate over both thyroid lobes
  3. Listen for a bruit

๐Ÿ‘จโ€โš•๏ธ Eponym

Named after Guttman, who described thyroid bruit as a marker of hypervascular thyrotoxicosis.

What is the most common cause of thyrotoxicosis?

Graves disease is caused by antibodies against?

What is the classical triad of Graves disease?

What is the most characteristic eye finding in Graves disease?

What is the most characteristic dermatological finding in Graves disease?


โญ High Yield Rapid Revision Table

Guttman SignTypeFindingClinical Significance
NoseClinical signIpsilateral nasal congestion after stellate ganglion blockIndicates successful sympathetic blockade
LarynxClinical testReversal of pitch changes on thyroid cartilage manipulationSuperior laryngeal nerve palsy
ThyroidClinical signThyroid bruit on auscultationGraves disease / thyrotoxicosis

๐Ÿง  Viva Pearls

  • Guttman sign has different meanings in ENT depending on the organ involved.
  • Nasal Guttman sign indicates successful stellate ganglion block.
  • Laryngeal Guttman sign evaluates superior laryngeal nerve function.
  • External branch of superior laryngeal nerve supplies the cricothyroid muscle.
  • Thyroid Guttman sign refers to a thyroid bruit, classically heard in Graves disease.
  • Graves disease is caused by antibodies against the TSH receptor.
  • Pretibial myxedema is specific for Graves disease.
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